Monoclonal antibodies are usually produced by:
A. Cultured T cells
B. Human plasma cells
C. Hybridomas
D. Cytotoxic T cells
The membranes of ion selective electrodes will determine which analyte is measured by
the electrode.
Chemistry
The selectivity of an ion-selective electrode is determined by the:
A. properties of the membrane used
B. solution used to fill the electrode
C. magnitude of the potential across the membrane internal reference electrode
D. type of glass used in electrode
Name the comprehensive written safety plan detailing the proper use and storage of hazardous chemicals in the workplace.
A. chemical hygiene plan
B. OSHA
C. SOP
D. MSDS
The ratio of blood to anticoagulant in a light blue stopper tube is:
A. 10:1
B. 9:1
C. 5:1
D. 2:1
Clostridium difficile is a gram-positive, spore-forming bacilli. The remaining organisms will all stain gram-negative on direct smear or smears made from culture. Which of the following organisms are gram-positive?
A. Neisseria gonorrhoeae
B. Brucella species
C. Clostridium difficile
D. Pseudomonas aeruginosa
Immunoassay is the most common technique that is used by clinical laboratories for
therapeutic drug monitoring.
Most of the drugs commonly assessed with TDM can be measured on analytical platforms
which utilize antibodies (in some form) for detection. Antibodies can be developed that
recognize drugs. Although most drugs are much too small to evoke an immune response,
scientists can conjugate drugs to immunogenic proteins to produce antibodies that
recognize drug-specific epitopes.
Which of the following is the most common technique that is used by clinical laboratories
for therapeutic drug monitoring?
A. Immunoassay
B. Electrophoresis
C. Atomic absorption
D. Ion selective electrode voltimetry
Platelets do not circulate in inactivated, spiny forms. The spiny, sticky form of the platelet is initiated once the platelets become activated in response to blood vessel damage. Which of the following is not true in terms of platelet characteristics?
A. Produced in the bone marrow by megakaryocytes.
B. Possess an inherent sticky property that aids in adhesion and aggregation.
C. Have a lifespan of roughly 9-12 days.
D. Are normally found circulating in their inactive, spiny form.
Alpha-fetoprotein is a substance typically used in the triple test during pregnancy and for screening chronic liver disease patients for hepatocellular carcinoma. Increased concentrations of alpha-fetoprotein (AFP) in adults are MOST characteristically associated with:
A. hepatocellular carcinoma
B. alcoholic cirrhosis
C. chronic active hepatitis
D. multiple myeloma
Gamma globulin (anti-D) is given to Rh-negative mothers to prevent any D antibody production, which could cause harmful effects in future pregnancies with an Rh-positive fetus. The administered anti-D will bind fetal Rh-positive cells that may come from the fetus in vivo; therefore the mother will not produce anti-D herself, preventing sensitization. A solution of gamma globulins containing anti-Rh (D) is given to an Rh (D) negative mother to:
A. Prevent fetal cells from initially sensitizing the mother
B. Neutralize any of the child's antibody that may have passed the placental barrier
C. Neutralize any natural maternal antibodies present
D. Prevent greater antibody response in a previously sensitized mother
Normocytic- G6PD deficiency, Malaria
Microcytic- Iron deficiency, Thalassemia
Macrocytic- Chronic Liver Disease, Vitamin B12 deficiency
Hematology
Match the disease conditions with appropriate red cell size classification
1. G6PD deficiency, Malaria
2. Iron deficiency, Thalassemia
3. Chronic Liver Disease, Vitamin B12 deficiency
A. Microcytic
B. Macrocytic
C. Normocytic
The recommended disinfectant for blood and body fluid contamination is:
A. sodium hydroxide.
B. antimicrobial soap.
C. hydrogen peroxide.
D. sodium hypochlorite.
Flow cytometry employs a combination of fluorescent antibody tagging of cells and analysis with laser light scatter. What principle(s) of flow cytometry are employed when performing immunophenotyping:
A. Defraction gradients
B. Impedance
C. Defraction gradients and impedance
D. Fluorescent antibody tagging and light scatter
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